日本の女性研究者

生物分子科学

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Asako Yamayoshi

 
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NameAsako Yamayoshi
URLhttp://www.hakubi.kyoto-u.ac.jp/eng/02_mem/06yamayoshi.shtml
AffiliationKyoto University
SectionGraduate School of Biomedical Sciences
Job titleAssociate Professor
DegreePh.D.(Kyoto Institute of Technology)
Other AffiliationGraduate School of Science, Kyoto University

Research Interests

 
DDS , 5-methyl-cytosine , microRNA , Development of Functional Molecule , Nucleic Acid Chemistry

Research Areas

 
  • Biomolecular science / Biomolecular chemistry / Nucleic Acid Chemistry

Academic & Professional Experience

 
Mar 2018
 - 
Today
Professor, Graduate School of Biomedical Sciences, Nagasaki University
 
Oct 2017
 - 
Today
Sakigake Researcher, さきがけ, JST
 
Apr 2015
 - 
Feb 2018
Associate Professor, The Hakubi Center for Advanced Research, Kyoto University
 
May 2007
 - 
Mar 2015
Assisitant Professor, Department of Biomolecular Engineering, Kyoto Institute of Technology
 
Mar 2007
 - 
May 2007
Assistant Professor, Department of Biomolecular Engineering, Kyoto Institute of Technology
 

Education

 
Jul 2003
 - 
Apr 2000
Department of Biomaterial Science, Graduate School of Science and Engineering, Kyoto Institute of Technology
 
Apr 1998
 - 
Mar 2000
Polymer Chemistry, Graduate School of Science and Engineering, Kyoto Institute of Technology
 
Apr 1994
 - 
Mar 1998
Polymer Chemistry, Faculty of Textile Science, Kyoto Institute of Technology
 
Mar 1993
 - 
Apr 1990
TOYONAKA SENIOR HIGH SCHOOL
 

Published Papers

 
Kobori Akio, Arai Taichiro, Sakata Yuya, Sugita Takayuki, Yamayoshi Asako, Murakami Akira
TETRAHEDRON LETTERS   59(41) 3690-3693   Oct 2018   [Refereed]
Photochromic DNA having fluorescent protein-inspired nucleosides
Akio Kobori, Taichiro Arai, Yuya Sakata, Takayuki Sugita, Asako Yamayoshi, Akira Murakami
Tetrahedron Letters   59(1) 3690-3693   Jul 2018   [Refereed]
Peptide Ribonucleic Acid (PRNA)–Arginine Hybrids. Effects of Arginine Residues Alternatingly Introduced to PRNA Backbone on Aggregation, Cellular Uptake, and Cytotoxicity
Hiroka Sugai, Ikuhiko Nakase, Seiji Sakamoto, Akihiro Nishio, Masahito Inagaki, Masaki Nishijima, Asako Yamayoshi, Yasuyuki Araki, Satoru Ishibashi, Takanori Yokota, Yoshihisa Inoue, and Takehiko Wada
Chemistry Letters   47(3) 381-384   Apr 2018   [Refereed]
Sugai Hiroka, Nakase Ikuhiko, Sakamoto Seiji, Nishio Akihiro, Inagaki Masahito, Nishijima Masaki, Yamayoshi Asako, Araki Yasuyuki, Ishibashi Satoru, Yokota Takanori, Inoue Yoshihisa, Wada Takehiko
CHEMISTRY LETTERS   47(3) 381-384   Mar 2018   [Refereed]
Ariyoshi J, Matsuyama Y, Kobori A, Murakami A, Sugiyama H, Yamayoshi A
Nucleic acid therapeutics   27(5) 303-308   Oct 2017   [Refereed]

Misc

 
Novel inhibitors targeting microRNA: Peptide-oligonucleotide conjugates for promotional releasing of microRNA from RISC
Ariyoshi Jumpei, Eimori Nao, Konishi Ryo, Akio Kobori, Akira Murakami, Asako Yamayoshi
THE INTERNATIONAL CHEMICAL CONGRESS OF ACIFIC BASIN SOCIETIES   1312-1312   Dec 2015   [Refereed]
Development of novel anti-HIV drugs that mimic functions of non-coding RNA
Asako Yamayoshi, Kodai Yoshimoto, Akio Kobori, Akira Murakami
THE INTERNATIONAL CHEMICAL CONGRESS OF ACIFIC BASIN SOCIETIES   1305-1305   Dec 2015   [Refereed]
Development of novel RISC inhibitors for promoting release of microRNA from RISC (II) The effects of chemical modifications of oligonucleotides on releasing of microRNA from RISC
Ariyoshi Jumpei, Eimori Nao, Konishi Ryo, Akio Kobori, Akira Murakami, Asako Yamayoshi
The 42nd International Symposium on Nucleic Acids Chemistry 2015   190-191   Sep 2015   [Refereed]
ホスホロアミダイト法を用いたRNA合成法
Antisense   12 3-15   2008   [Refereed][Invited]
機能化アンチセンス核酸の現状と展望 ~ photodynamic antisense therapy ~
11 3-16   2006   [Refereed][Invited]

Books etc

 
Current Protocols in Nucleic Acid Chemistry
A. Kobori, A.Yamayoshi, A. Murakami (Part:Contributor, Synthesis of oligonucleotides containing 4,5’,8-trimethylpsoralen at the 2'-O position and their cross-linking properties with RNAs)
Wiley Interscience   Sep 2014   
Biomedical Polymers and Polymer Therapeutics
A. Murakami, A.Yamayoshi, R.Iwase, J.Nishida, T.Yamaoka, and N.Wake (Part:Contributor, Photodynamic Antisense Regulation of Human Cervical Carcinoma Cell)
Kluwer Academic/Plenum Publishers   Jun 2001   
Phoregulation of DNA/RNA functions
A.Yamayoshi, A. Kobori, A. Murakami (Part:Contributor, Photo-dynamic antisense regulation by photo-cross-linkable antisense oligonucleotides)
Pan Stanford Publishing Pte. Ltd.   

Conference Activities & Talks

 
エクソソーム随伴導入型薬物送達システムの開発
Asako Yamayoshi
日本薬学会第139回年会   22 Mar 2019   
光をトリガーとした遺伝子発現制御法の開発 [Invited]
Asako Yamayoshi
第3期 第4回 レーザー学会「レーザーバイオ医療」技術専門委員会   8 Mar 2019   
遺伝子の非コード領域の機能制御を目指した人工核酸の開発
Asako Yamayoshi
アライアンス・展開Bプロジェクト「DNAのエピジェネティック修飾を標的とした新規遺伝子制御分子の開発」と科研費特別推進研究「リピート結合分子をプローブとしたトリヌクレオチドリピート病の化学生物学研究」に関連する核酸科学ミニシンポジウム   7 Jan 2019   
Development of novel photoresponsive olugonucleotides targeting epigenetic DNA modifications [Invited]
Asako Yamayoshi
China-Japan Joint Symposium on Biomaterials 2018(   30 Nov 2018   
Functional Regulation of Epigenetic DNA Modifications using Photoreactive Oligonucleotides
Asako Yamayoshi, Takayuki Shibata, Yui Sakai, Takeshi Yamada, Tsuyoshi Yamamoto, Takehiko Wada, Kazuhiko Nakatani
The 45nd International Symposium on Nucleic Acids Chemistry   7 Nov 2018   

Association Memberships

 
THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER , THE JAPANESE BIOCHEMICAL SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

Research Grants & Projects

 
Novel photodynamic approaches to control epigenetic gene regulation
JST: Sakigake
Project Year: Oct 2017 - Mar 2021    Investigator(s): Asako Yamayoshi
Kyoto University: GAP Foundation
Project Year: Apr 2017 - Mar 2018    Investigator(s): Asako Yamayoshi