日本の女性研究者

神経科学

Researcher List >> YOKOYAMA Utako
 

YOKOYAMA Utako

 
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NameYOKOYAMA Utako
DegreeMedical doctor(Tokyo Women's Medical University)

Research Interests

 
cAMP

Research Areas

 
  • Clinical internal medicine / Cardiovascular medicine / 
  • Clinical internal medicine / Embryonic/Neonatal medicine / 
  • Clinical internal medicine / Pediatrics / 
  • Basic medicine / General pharmacology / 
  • Basic medicine / General physiology / 

Academic & Professional Experience

 
 
   
 
Associate Professor, Yokohama City University School of Medicine Medical Course Graduate School of Medicine Degree Program
 

Education

 
 
 - 
1994
Faculty of Medicine, Okayama University
 

Awards & Honors

 
Apr 2014
血管の分化発達の病態生理の解明とその分子標的治療の確立, JPS Scientific Research Award, Japan Pediatric Society
 
Apr 2011
動脈管閉鎖の分子機序の解明, The 23th Yokohama City University Medical Association Award, Yokohama City University Medical Association
 
Jul 2009
Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A., The 5th HIROSI KURIYAMA AWARD, The Japan Society of Smooth Muscle Research
 
Mar 2009
The Cyclic AMP Effector Epac Integrates Pro- and Anti-Fibrotic Signals, 2nd Woman Researcher's Award, The Japanese Circulation Society
 
Jun 2008
Young Investigator's Award
 
Apr 2007
Postdoctoral fellow Travel Award, American Society for Biochemistry and Melecular Biology
 
Mar 2007
UC San Diego Cardiovascular Scholarship Award, University of California, San Diego
 
Apr 2006
Prostaglandin Promotes Hyaluronic Acid-Induced Neointimal Formation in Ductus Arteriosus, 1st Pediatric Cardiology Award, The Japanese Circulation Society
 
Mar 2007
Vascular Injury-induced Upregulation of Epac1 Counteracts PKA, Promoting Smooth Muscle Cell Migration and Neointimal Thickening, 24th Young Investigator's Award, The Japanese Circulation Society
 

Published Papers

 
The usefulness of exchanged protein directly activated by cAMP (Epac)1-inhibiting therapy for prevention of atrial and ventricular arrhythmias in mice
Prajapati R, Fujita T, Suita K, Nakamura T, Cai W, Hidaka Y, Umemura M, Yokoyama U, Knollmann B, Okumura S, Ishikawa Y.
Circulation journal      2019   [Refereed]
Yokoyama U, Arakawa N, Ishiwata R, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Matsumoto M, Koizumi N, Taguri M, Hirano H, Yoshimura K, Ogino H, Masuda M, Ishikawa Y
American journal of physiology. Heart and circulatory physiology   315(4) H1012-H1018   Jul 2018   [Refereed]
Mamun A, Yokoyama U, Saito J, Ito S, Hiromi T, Umemura M, Fujita T, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Masuda M, Ishikawa Y
Physiological reports   6(18) e13878   Sep 2018   [Refereed]
Umemura M, Islam MR, Fukumura H, Sato I, Kawabata Y, Matsuo K, Nakakaji R, Nagasako A, Ohtake M, Fujita T, Yokoyama U, Nakayama T, Eguchi H, Ishikawa Y
Cancer science      Oct 2018   [Refereed]
Fujita T, Umemura M, Yokoyama U, Okumura S, Ishikawa Y
Cellular and molecular life sciences : CMLS   74(4) 1-16   Aug 2016   [Refereed]

Misc

 
東野展也, 金子真, 横山詩子, 石川義弘
日本機械学会ロボティクス・メカトロニクス講演会講演論文集(CD-ROM)   2016 ROMBUNNO.2A2‐20a1   Jun 2016
横山詩子, 石渡遼, 石川義弘
日本生理学雑誌(Web)   78(3) WEB ONLY   May 2016
石渡遼, 横山詩子, 市川泰広, 黒滝大翼, 田村智彦, 石川義弘
日本循環制御医学会総会(Web)   37th 40   2016
MASUDA Taisuke, UKIKI Mitsuhiro, MATSUSAKI Michiya, AKASHI Mitsuru, YOKOYAMA Utako, ARAI Fumihito
The Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec)   2016(0) 2A2-20a3   2016
<p>We propose a fabrication method of artificial small blood vessel constructs via a layer-by-layer cellular assembly technique using smooth muscle cells, the construction of a biodegradable scaffold, and integration in a microfluidic perfusion cu...
HIGASHINO Nobuya, KANEKO Makoto, YOKOYAMA Utako, ISHIKAWA Yoshihiro
The Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec)   2016(0) 2A2-20a1   2016
<p>When we apply cyclic pressure to smooth muscle cells as if humans do muscle training, the cellular tissue becomes stiffer. We call applying such cyclic pressure to cells in order to make stiff cellular tissue "Cell Exercise". The goal of this s...

Conference Activities & Talks

 
How ”Human arterial graft” should be fabricated?
YOKOYAMA Utako
CBS 2018- IEEE International Conference on Cyborg and Bionic Systems   27 Oct 2018   
Uncovering new GPCR signaling pathways in Prostaglandin E2-mediated vascular remodeling and inflammation
YOKOYAMA Utako
The 9th Federation of the Asian and Oceanian Physiological Societies Congress   30 Mar 2018   
Cardiac-Specific Overexpression of Caveolin-3 Induces Endogenous Cardiac Protection.
2007   
Blockade of T-type Calcium Channels Attenuates Smooth Muscle Cell Migration, Neointimal Formation, and Oxygen-induced Vascular Contraction in Rat Ductus Arteriosus.
2007   
cAMP-dependent Intimal Cushion Formation of the Rat Ductus Arteriosus: The Role of Epac.
2007   

Association Memberships

 
THE JAPANESE PHARMACOLOGICAL SOCIETY , JAPANESE SOCIETY OF PATHOPHYSIOLOGY , Japan Pediatric Society , The Japanese Circulation Society , Japanese Society of Pediatric Cardiology and Cardiac Surgery , Physiological Society of Japan , Japan Society of Smooth Muscle Research , The Japanese Heart Failure Society , The Society of Cardiovascular Endocrinology and Metabolism , American Heart Association

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(挑戦的萌芽研究)
Project Year: 2012 - 2013    Investigator(s): Utako YOKOYAMA
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2011 - 2013    Investigator(s): Susumu MINAMISAWA
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2010 - 2012    Investigator(s): Rika AOKI
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2010 - 2012    Investigator(s): Shinichi SUZUKI
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2009 - 2011    Investigator(s): Utako YOKOYAMA