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生物学

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YAMAZAKI Mami

 
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NameYAMAZAKI Mami
AffiliationChiba University
Job titleChiba University
DegreePh. D. of Pharmaceutical Sciences(Chiba University)
ORCID ID0000-0001-6157-5287

Research Interests

 
Myc , WD , MYB , Perilla frutescens , RNAi , Plant molecular biology , Pharmacognosy , Secondary metabolism , Biosynthesis , Alkaloid , Envionmental Pharmaceutics

Research Areas

 
  • Pharmacy / Environmental pharmacy / 
  • Basic biology / Plant molecular biology/Plant physiology / 
  • Genome science / Applied Genomics / 
  • Biomolecular science / Biomolecular science / 
  • Pharmacy / Chemical pharmacy / 

Education

 
Apr 1986
 - 
Mar 1991
Graduate School of Pharmaceutical Sciences, Chiba University
 
Apr 1982
 - 
Mar 1986
Faculty of Pharmaceutical Sciences, Chiba University
 

Awards & Honors

 
Sep 2017
Informatics framework of traditional Sino-Japanese medicine (Kampo) unveiled by factor analysis, J Nat Med (2016) 70:107-114, Best paper award of Japanese Society of Pharmacognosy
 
1998
Prize for the best poster at the Phytochemical Society fo Europe, Future Trends in Phytochemistry meeting, Phytochemical Society of Europe
 
Sep 2018
De novo transcriptome assembly and characterization of nine tissues of Lonicera japonica to identify potential candidate genes involved in chlorogenic acid, luteolosides, and secoiridoid biosynthesis pathways, Best paper award of Japanese Society of Pharmacognosy
 
 
The 21st award for best paper in Plant Cell Physiolosy
 

Published Papers

 
Sato H, Mitsuhashi T, Yamazaki M, Abe I, Uchiyama M
Angewandte Chemie (International ed. in English)      Sep 2018   [Refereed]
Nakashima Y, Mitsuhashi T, Matsuda Y, Senda M, Sato H, Yamazaki M, Uchiyama M, Senda T, Abe I
Journal of the American Chemical Society   140(30) 9743-9750   Aug 2018   [Refereed]
Sato H, Uchiyama M, Saito K, Yamazaki M
Metabolites   8(3)    Aug 2018   [Refereed]
Ohnishi Miwa, Anegawa Aya, Sugiyama Yuko, Harada Kazuo, Oikawa Akira, Nakayama Yasumune, Matsuda Fumio, Nakamura Yukiko, Sasaki Ryosuke, Shichijo Chizuko, Hatcher Patrick G., Fukaki Hidehiro, Kanaya Shigehiko, Aoki Koh, Yamazaki Mami, Fukusaki Eiichiro, Saito Kazuki, Mimura Tetsuro
PLANT AND CELL PHYSIOLOGY   59(7) 1353-1362   Jul 2018   [Refereed]
Sato Hajime, Wang Chao, Yamazaki Mami, Saito Kazuki, Uchiyama Masanobu
PLOS ONE   13(6)    Jun 2018   [Refereed]
Yamazaki Mami, Rai Amit, Yoshimoto Naoko, Saito Kazuki
PLANT BIOTECHNOLOGY REPORTS   12(2) 69-75   Apr 2018   [Refereed]
Sato Hajime, Narita Koji, Minami Atsushi, Yamazaki Mami, Wang Chao, Suemune Hironori, Nagano Shingo, Tomita Takeo, Oikawa Hideaki, Uchiyama Masanobu
SCIENTIFIC REPORTS   8    Feb 2018   [Refereed]
山崎真巳
アグリバイオ   2(1) 8‐12   Jan 2018
Narita Koji, Sato Hajime, Minami Atsushi, Kudo Kosei, Gao Lei, Liu Chengwei, Ozaki Taro, Kodama Motoichiro, Lei Xiaoguang, Taniguchi Tohru, Monde Kenji, Yamazaki Mami, Uchiyama Masanobu, Oikawa Hideaki
ORGANIC LETTERS   19(24) 6696-6699   Dec 2017   [Refereed]
Rai Megha, Rai Amit, Kawano Noriaki, Yoshimatsu Kayo, Takahashi Hiroki, Suzuki Hideyuki, Kawahara Nobuo, Saito Kazuki, Yamazaki Mami
MOLECULES   22(12)    Dec 2017   [Refereed]
Rai Amit, Saito Kazuki, Yamazaki Mami
PLANT JOURNAL   90(4) 764-787   May 2017   [Refereed]
Saga Yusuke, Araki Takeshi, Araya Hiroshi, Saito Kazuki, Yamazaki Mami, Suzuki Hideyuki, Kushiro Tetsuo
ORGANIC LETTERS   19(3) 496-499   Feb 2017   [Refereed]
Rai Amit, Kamochi Hidetaka, Suzuki Hideyuki, Nakamura Michimi, Takahashi Hiroki, Hatada Tomoki, Saito Kazuki, Yamazaki Mami
JOURNAL OF NATURAL MEDICINES   71(1) 1-15   Jan 2017   [Refereed]
Bunsupa Somnuk, Yamazaki Mami, Saito Kazuki
MINI-REVIEWS IN MEDICINAL CHEMISTRY   17(12) 1002-1012   2017   [Refereed]
Fukushima Atsushi, Nakamura Michimi, Suzuki Hideyuki, Yamazaki Mami, Knoch Eva, Mori Tetsuya, Umemoto Naoyuki, Morita Masaki, Hirai Go, Sodeoka Mikiko, Saito Kazuki
FRONTIERS IN PLANT SCIENCE   7    Dec 2016   [Refereed]
Udomsom Nirin, Rai Amit, Suzuki Hideyuki, Okuyama Jun, Imai Ryosuke, Mori Tetsuya, Nakabayashi Ryo, Saito Kazuki, Yamazaki Mami
FRONTIERS IN PLANT SCIENCE   7    Dec 2016   [Refereed]
Rai Amit, Nakamura Michimi, Takahashi Hiroki, Suzuki Hideyuki, Saito Kazuki, Yamazaki Mami
PLANT CELL REPORTS   35(10) 2091-2111   Oct 2016   [Refereed]
Bunsupa Somnuk, Hanada Kousuke, Maruyama Akira, Aoyagi Kaori, Komatsu Kana, Ueno Hideki, Yamashita Madoka, Sasaki Ryosuke, Oikawa Akira, Saito Kazuki, Yamazaki Mami
PLANT PHYSIOLOGY   171(4) 2432-2444   Aug 2016   [Refereed]
山崎真巳
和漢薬   (756) 2‐4   May 2016
Rai Amit, Yamazaki Mami, Takahashi Hiroki, Nakamura Michimi, Kojoma Mareshige, Suzuki Hideyuki, Saito Kazuki
FRONTIERS IN PLANT SCIENCE   7    Apr 2016   [Refereed]

Misc

 
山崎真巳, 金谷重彦, 岡田岳人
国際化に対応した科学的視点に立った日本漢方診断法・処方分類および用語の標準化の確立 平成25年度 総括・分担研究報告書   116-118   2014
山崎真巳
創薬等ヒューマンサイエンス総合研究事業 平成10年度 若手研究者奨励研究報告   97-99   1999
Molecular cloning and biochemical characterization of a novel anthocyanin 5-O-glucosyltransferase by mRNA differential display for plant formas regarding anthocyanin. (共著)
Lupin alkaloids in tissue culture of ┣DBSophora flavescens(/)-┫DB var. ┣DBangustifolia(/)-┫DB : Greening induced production of martin. (共著)
Greening induced production of (+)-lupanine in tissue culture of ┣DBThermopsis lupinoides(/)-┫DB. (共著)
Stable transfer and expression of chimeric genes in licorice (┣DBGlycyrrhiza uralensis(/)-┫DB) using an Ri plasmid binary vector. (共著)
Genetic transformation of foxglove (┣DBDigitalis purpurea(/)-┫DB) by chimeric foreign genes and production of cardioactive glycosides. (共著)
Metabolism of solanaceous alkaloids in transgenic plant teratomas integrated with genetically engineered genes. (共著)
Tissue specific and stress-inducible expression of the TR promoter for mannopine synthase in transgenic medicinal plants. (共著)
Transgenic medicinal plants : ┣DBAgrobacterium(/)-┫DB-mediated foreign gene transfer and production of secondary metabolites. (共著)
Transgenic herbicide-resistant ┣DBAtropa belladonna(/)-┫DB using Ri-binary vector and inheritance of the transgenic trait. (共著)
Molecular cloning and bacterial expression of dDNA encoding a plant cysteine synthase(共著)
Genetic relationships among ┣DBGlycyrrhiza(/)-┫DB plants determined by RAPD and RFLP analyses. (共著)
Extraction of DNA and RAPD analysis from dried ┣DBlicorice root(/)-┫DB(共著)
Transgenic fertile ┣DBScoparia dulcis(/)-┫DB L. , a folk medicinal plant, Conferred with a herbicide-resistant trait using an Ri binary vector(共著)
Regulation of sulfur assimilation in higher plants : A sulfate transporter induced in sulfate-starved roots plays a central role in ┣DBArabidopsis thaliana(/)-┫DB. (共著)
Cloning and molecular analysis of structural genes involved in anthocyanin biosynthesis and expressed in a forma-specific manner in ┣DBPerilla frutescens(/)-┫DB. (共著)
Transformation of ┣DBPerilla frutescens(/)-┫DB var. ┣DBcrispa(/)-┫DB using an ┣DBAgrobacterium(/)-┫DB-Ri binary vector system(共著)
Random amplified polymorphic DNA and restriction fragment length polymorphism analyses of ┣DBCannabis sativa(/)-┫DB(共著)

Books etc

 
Natural Products: Discourse, Diversity, and Design
Supaart Sirikantaramas, Mami Yamazaki, and Kazuki Saito (Part:Contributor, How plants avoid the toxicity of self-produced defense bioactive compounds.)
Wiley-Blackwell, Oxford   2014   
Advances in Botanical Research vol. 68, Nathalie Giglioli-Guivarc'h, ed.
Supaart Sirikantaramas, Mami Yamazaki, Kazuki Saito (Part:Contributor, Chapter Five - Camptothecin: Biosynthesis, biotechnological production and resistance mechanism(s).)
Academic Press   2013   
Medicinal Plant Biotechnology: From Basic Research to Industrial Applications, O. Kayser and W. J. Quax, eds.
Takashi Asano, Hiroshi Sudo, Mami Yamazaki, and Kazuki Saito (Part:Contributor, Camptothecin production in cell cultures of Ophiorrhiza species.)
Wiley-VCH Verlag GmbH, Weinheim, Germany   2008   
Methods in Molecular Biology, vol. 317, Differential Display Methods and Protocols
Mami Yamazaki and Kazuki Saito (Part:Contributor, Isolation and characterization of anthocyanin 5-O- glucosyltransefrase in Perilla frutescens var. crispa by differential display)
Humana Press Inc., Totowa, NJ   2006   
Plant Response to Environments: Molecular Mechanism and Application to Biotechnology. Jin Murata and Dong-Hee Lee, eds.
Kazuki Saito, Mami Yamazaki, Zhizhong Gong, Emiko Yamagishi and Sompornpailin Kanokporn (Part:Contributor, Molecular mechanism and regulation of anthocyanin formation in two different chemotypes of Perilla.)
The Botanical Society of Japan, Tokyo   2000   
Biotechnology in Agriculture and Forestry, Vol. 45 Transgenic Medicinal Plants. ed. by Y.P.S. Bajaj
Mami Yamazaki and Kazuki Saito (Part:Contributor, Genetic transformation of Glycyrrhiza ularensis (Licorice) and related species.)
Springer-Verlag, Berlin   1999   
PERILLA The Genus Perilla. ed. by H-C Yu, K. Kosuna and M. Haga, eds.
Mami Yamazaki, Zhizhong Gong and Kazuki Saito (Part:Contributor, Molecular biology in Perilla frutescens: Isolation of specifically expressed genes in chemotypes.)
Harwood Academic Publishers, Amsterdam   1997   
Biotechnology in Agriculture and Forestry, Vol. 36 Somaclonal Variation in Crop Improvement II. Y.P.S. Bajaj ed.
Mami Yamazaki and Kazuki Saito (Part:Contributor, In vitro induction of herbicide resistance in Atropa belladonna L.)
Springer-Verlag, Berlin   1996   
Biotechnology in Agriculture and Forestry, Vol. 26 Medicinal and Aromatic Plants VI ed. by Y.P.S. Bajaj
Mami Yamazaki, Isamu Murakoshi and Kazuki Saito (Part:Contributor, Thermopsis lupinoides (Japanese name 'Sendai-hagi'): In vitro culture and production of lupin alkaloids.)
Springer-Verlag, Berlin   1994   
Biotechnology in Agriculture and Forestry, Vol. 22 Plant Protoplasts and Genetic Engineering III ed by Y.P.S. Bajaj
Kazuki Saito, Mami Yamazaki, Koichiro Shimomura, Kayo Yoshimatsu and Isamu Murakoshi (Part:Contributor, Genetic transformation in Digitalis purpurea L. (Foxglove).)
Springer-Verlag, Berlin   1993   
Biotechnology in Agriculture and Forestry, Vol. 24 Medicinal and Aromatic Plants V. Y.P.S. Bajaj ed.
Kazuki Saito, Mami Yamazaki and Isamu Murakoshi (Part:Contributor, Sophora flavescens (Kurara): In vitro culture and production of lupin alkaloids.)
Springer-Verlag, Berlin   1993   
Plant Tissue Culture and Gene Manipulation for Breeding and Formation of Phytochemicals. K. Ohno et al. eds.
Kazuki Saito, Naoko Miura, Mami Yamazaki and Isamu Murakoshi (Part:Contributor, Isolation and sequence analysis of cDNA encoding cysteine synthase from spinach (Spinacia oleracea).)
National Institute of Agrobiological Resources, Tsukuba   1992   

Conference Activities & Talks

 
Yamazaki Mami, Higuchi Mari, Wangwattana Bunyapa, Saito Kazuki
Supplement   11 Mar 2011   
A pigmentation of aerial parts of <I>Perilla frutescens</I> var. <I>crispa</I> has been good subject in genetics. So far, it has been found that A, B and K loci regulate anthocyanin production in leaf and stem. Recently, it has been shown that a t...
山崎真巳
天然薬物の開発と応用シンポジウム講演要旨集   2 Nov 2010   
千葉基晶, 浅野孝, 奥山淳, 斉藤和季, 山崎真巳
日本植物細胞分子生物学会大会・シンポジウム講演要旨集   2 Sep 2010   
鹿倉友美子, BUNSPA Somnuk, 斉藤和季, 山崎真巳
日本植物細胞分子生物学会大会・シンポジウム講演要旨集   2 Sep 2010   
榊原圭子, 中林亮, 福島敦史, 松田史生, 井上恵理, 菅原聡子, 黒森崇, 伊藤卓也, 篠崎一雄, WANGWATTANA Bunyapa, 山崎真巳, 斉藤和季
日本植物細胞分子生物学会大会・シンポジウム講演要旨集   2 Sep 2010   
千葉基晶, 浅野孝, 奥山淳, 斉藤和季, 山崎真巳
日本薬学会年会要旨集   5 Mar 2010   
Yamazaki Mami, Asano Takashi, Kashihara Emi, Kobayashi Kanae, Sasaki Ryosuke, Iijima Yoko, Aoki Ko, Shibata Daisuke, Saito Kazuki
12 Mar 2010   
Camptothecin is produced in the hairy roots but not in cell suspension culture of <I>Ophiorrhiza pumila</I>. The hairy root specific metabolites were profiled by non-target analysis by using infusion FT-ICR-MS. Furthermore, the gene expression of ...
Nakabayashi Ryo, Yonekura-Sakakibara Keiko, Matsuda Fumio, Tohge Takayuki, Kitajima Mariko, Takayama Hiromitsu, Yamazaki Mami, Saito Kazuki
Supplement   12 Mar 2010   
In Arabidopsis, flavonoid biosynthesis is regulated by MYB transcription factors such as MYB75/PAP1 for anthocyanin and MYB12 for flavonol. We have generated the transgenic lines over-expressing both PAP1 and MYB12 (WOX1-1,2) (1) to characterize t...
柏原恵美, 浅野孝, 千田かおり, 佐々木亮介, 飯島陽子, 青木考, 柴田大輔, 斉藤和季, 山崎真巳
日本植物細胞分子生物学会大会・シンポジウム講演要旨集   29 Jul 2009   
片山賀惠, BUNSUPA Somnuk, 斉藤和季, 山崎真巳
日本植物細胞分子生物学会大会・シンポジウム講演要旨集   29 Jul 2009   
小林可菜英, 浅野孝, 佐々木亮介, 飯島陽子, 青木考, 柴田大輔, 斉藤和季, 山崎真巳
日本植物細胞分子生物学会大会・シンポジウム講演要旨集   29 Jul 2009   
山崎真巳
日本植物細胞分子生物学会大会・シンポジウム講演要旨集   29 Jul 2009   
Yonekura-Sakakibara Keiko, Inoue Eri, Matsuda Fumio, Wangwattana Bunyapa, Yamazaki Mami, Saito Kazuki
Supplement   16 Mar 2009   
In plants, most of genes involved in metabolism belong to multigene families. It was reported that there are 272 cytochrome P450 genes and 107 family glycosyltransferase genes in <I>Arabidopsis</I>. Their huge diversity makes it difficult to deter...
中林亮, 榊原圭子, 松田史生, 峠隆之, 北島満里子, 高山廣光, 山崎真巳, 斉藤和季
日本薬学会年会要旨集   5 Mar 2009   
Yamazaki Mami, Okuyama Jun, Hayashi Kayoko, Asano Takashi, Sirikantaramas Supaart, Saito Kazuki
Supplement   2008   
A monoterpene-indole alkaloid, camptothecin (CPT), is produced in hairy roots but not in dedifferentiated cell-suspension culture of <I> Ophiorriza pumila </I>. Using these systems, the genes specifically expressed in CPT-producing hairy roots wer...
Ikeura Emi, Okada Taketo, Saito Kazuki, Yamazaki Mami
Supplement   Mar 2007   
Quinolizidine alkaloids, referred to as lupine alkaloids, occur primarily in the genus Lupinus. <I>Lupinus angustifolius</I> L. cultivated as a crop has a sweet cultivar cv. Uniharvest and a bitter cultivar cv. Fest. In this study, we profiled the...
北島満里子, 米山崇子, 小暮紀行, 浅野孝, 須藤浩, 山崎真巳, 斉藤和季, 相見則郎, 高山広光
日本薬学会年会要旨集   6 Mar 2006   
林宏明, 岸本菜緒子, 高屋優一, 岡野陽平, 井上謙一郎, 飯沼宗和, 須藤浩, 山崎真巳, 斉藤和季
日本薬学会年会要旨集   6 Mar 2006   
Nishiyama Yasutaka, Tohge Takayuki, Tanaka Yoshikazu, Taguchi Goro, Fuell Christine, Michael Anthony, Kitayama Masahiko, Yamazaki Mami, Saito Kazuki
Supplement   Mar 2006   
In <I>PAP1</I>-overexpressing mutants, anthocyanins and quercetin-type flavonol glycosides are specifically over-accumulated. Microarray analyses revealed that expressions of 38 genes are higher than in wild type. Acyltransferases (ATs), whose fun...

Association Memberships

 
THE JAPANESE SOCIETY OF PLANT PHYSIOLOGISTS

Patents

 
3870234